ABSTRACT
We used 2 commercially available antibody tests to estimate seroprevalence of severe acute respiratory syndrome coronavirus 2 infection in Japan during June 2020. Of 7,950 samples, 8 were positive by both assays. Using 2 reliable antibody tests in conjunction is an effective method for estimating seroprevalence in low prevalence settings.
Subject(s)
Antibodies, Viral/blood , COVID-19 Serological Testing/statistics & numerical data , COVID-19/epidemiology , SARS-CoV-2/immunology , Adult , Aged , COVID-19/blood , COVID-19/immunology , Female , Humans , Japan , Male , Middle Aged , Prevalence , Seroepidemiologic Studies , Young AdultABSTRACT
We encountered two female patients with COVID-19 Eone transferred from the cruise ship, Diamond Princess, docked in the Yokohama port, and the other with community transmission of the infection. The former patient had asymptomatic pneumonia, which subsided spontaneously. The latter patient suffered from severe rapidly worsening pneumonia which necessitated mechanical ventilation and extracorporeal membrane oxygenation, but eventually showed complete resolution of the disease. Although the lung involvement in those two cases at their first evaluation seemed to be equal, they exhibited very different clinical courses Eone showing self-limiting asymptomatic pneumonia and the other showing severe progressive pneumonia.